Two appliances and crews attended from High Wycombe, along with one officer.
The collision had taken place close to the junction of Water End Road.
One man and one woman were released and in the care of South Central Ambulance Service, before they arrived. Two women were released, uninjured, before they arrived.
The firefighters used a Tirfor winch to help make the scene safe and return an overturned vehicle onto its wheels.
Thames Valley Air Ambulance and Thames Valley Police also attended.
A Tirfor winch is a hand operated pulling and lifting winch.