Two appliances and crews from Thame and one from Kidlington attended, along with an officer.
The firefighters used hydraulic rescue equipment to release one woman, injured, who was passed into the care of South Central Ambulance Service. A second woman was cared for by the ambulance service, and three further women and three men were uninjured.
The firefighters made the vehicles safe and used an environmental pack.
Thames Valley Air Ambulance and Thames Valley Police also attended.