One appliance and crew from Buckingham and one from West Ashland attended, along with two officers.
Three plastic five litre canisters, emitting vapour, were found in the road. The road was closed while the firefighters worked to identify the substance they contained.
The substance was confirmed as 14 per cent hydrochloric acid. The road required professional cleaning and remained closed until this had taken place.
Thames Valley Police were also in attendance.