One appliance and crew from Broughton and one from West Ashland attended, along with an officer.
One man, one woman, one girl and one boy, all suffering minor injuries, were out when the firefighters arrived.
Two further women were being cared for by South Central Ambulance Service.
The road was closed while they worked at the scene.
The firefighters made the scene safe and left the incident in the hands of Thames Valley Police.