One appliance and crew from Marlow, one from High Wycombe, along with an officer attended.
A road collision involving one car ending up on its side took place.
Prior to the firefighters arriving, three people were released uninjured, a man was also released injured.
A full road closure was put in place.
The firefighters used an immediate emergency care kit and provided oxygen therapy.
South Central Ambulance Service and Thames Valley Police also attended.