One appliance and crew from Broughton, one from Newport Pagnell and one from West Ashland attended, along with an officer.
The firefighters provided immediate emergency care to one man, injured, before passing him into the care of South Central Ambulance Service. A second man was out of the vehicle he had been traveling in, uninjured, before they arrived.
The motorway was closed while they worked at the scene.
National Highways also attended.
