Two appliances and crews from Aylesbury, along with an officer attended.
A road collision involving two cars took place.
Two men were out of the cars on arrival.
The firefighters used hydraulic rescue equipment to release a woman who had become trapped, injured, passing her into the care of the South Central Ambulance Service.
They also used an environmental pack to help stem a fluid leak.
There was a road closure put in place, and the incident was left in the hands of Thames Valley Police.