One appliance and crew from Langley, two from Slough, and a water carrier from Bracknell attended, along with one officer.
Smoke was issuing from the trailer compartment of a lorry when they arrived.
The lorry was relocated to the hard shoulder of Junction 1 of the M40 and its load of mixed waste was unloaded, so firefighters could extinguish the fire.
Firefighters used two sets of breathing apparatus and one hose reel. National Highways also attended and closed two lanes of the motorway.